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Analysis of the Surgical Outcome of Free Flap Reconstruction in Critical Limb-threatening Ischemia
- Subtitle
- Focusing on Endovascular Timing
- Author(s)
- 한형민
- Alternative Author(s)
- Hyung Min Hahn
- Advisor
- 이일재
- Department
- 일반대학원 의학과
- Publisher
- The Graduate School, Ajou University
- Publication Year
- 2022-02
- Language
- eng
- Keyword
- Angioplasty; Critical limb-threatening ischemia; Free flap; Lower extremity reconstruction; Peripheral arterial disease
- Alternative Abstract
- Background: Arterial revascularization and free flap reconstruction is safe and effective for limb salvage in patients with critical limb-threatening ischemia. This study aimed to determine whether reconstruction outcomes were affected by the time interval between endovascular treatment and free flap transfer in lower extremity reconstruction for critical limb ischemia. Methods: Patients who underwent endovascular intervention and subsequent free flap reconstruction with > 6 months of follow-up were reviewed. Those with wounds with oncological and traumatic etiologies were excluded. Patients’ demographics, risk factors, details of microsurgical procedures, details of endovascular intervention, and flap outcomes were collected. Results: Overall, 64 consecutive patients (M:F = 50:14 and mean age, 57.3 [range, 29–82] years) were evaluated between November 2011 and October 2019. Angioplasty failed in three patients. For soft-tissue reconstruction, anterolateral free flaps were used most frequently (n = 54 and 84.4%). Flap-related complications developed in 12 cases, of which five cases included total flap necrosis. The interval between endovascular intervention and free flap transfer was not associated with flap loss in multivariate regression analysis. Patients with kidney transplants and higher serum creatinine were associated with total flap necrosis. Advanced age, failed angioplasty, and perfusion status of the pedal arch were associated with major flap complications. Conclusion: Our study revealed that the interval between endovascular intervention and free flap transfer was not associated with flap loss.
- Fulltext
- Appears in Collections:
- Graduate School of Ajou University > Department of Medicine > 4. Theses(Ph.D)
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