Stereoselective Total Synthesis of (–)-Hedycoropyran A

Author(s)
안병연
Advisor
이동주
Department
일반대학원 약학과
Publisher
The Graduate School, Ajou University
Publication Year
2022-02
Language
eng
Keyword
(–)-Hedycoropyran ADehydrogenative CycloetherificationDiastereoselectivityNatural Producttrans-2-Alkyl-6-aryl-36-dihydro-2H-pyran
Alternative Abstract
The second stereoselective total synthesis of (–)-hedycoropyran A (1) has been accomplished in 10 steps with 4.73% overall yield from the readily available alkene 6. The key features of our strategy include (1) highly diasteoreoselective construction of trans-2-alkyl-6-aryl-3,6-dihydro-2H-pyran framework and (2) substrate-controlled trans-dihydroxylation at C(3)/C(4)
URI
https://dspace.ajou.ac.kr/handle/2018.oak/21315
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Graduate School of Ajou University > Department of Pharmacy > 3. Theses(Master)
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