repository
Prognostic reappraisal of postoperative carcinoembryonic antigen in T1-2N0 colorectal cancer
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 오승엽 | - |
| dc.contributor.author | PIAN GUANGZHE | - |
| dc.date.accessioned | 2022-11-29T02:33:07Z | - |
| dc.date.available | 2022-11-29T02:33:07Z | - |
| dc.date.issued | 2022-02 | - |
| dc.identifier.other | 31353 | - |
| dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/20594 | - |
| dc.description | 학위논문(박사)--아주대학교 일반대학원 :의학과,2022. 2 | - |
| dc.description.tableofcontents | Ⅰ. INTRODUCTION 1 Ⅱ. PATIENTS AND METHODS 4 A. Patients 5 B. Data collection 5 C. Statistical analysis 7 Ⅲ. RESULTS 9 A. Clinicopathological features 10 B. Survival analysis based on the preoperative and postoperative CEA cut-off value of 5.0 ng/ml 13 C. Re-determined the cut-off value of preoperative and postoperative CEA 15 D. Survival analysis according to the new cut-off values 17 E. Univariate and multivariate analyses for OS and DFS 20 F. Survival analysis of postoperative CEA in colon and rectal cancer 26 G. Survival analysis based on CEA changes 28 H. The relationship between postoperative CEA and clinicopathological features 31 Ⅳ. DISCUSSION 34 Ⅴ. CONCLUSION 40 REFERENCES 42 | - |
| dc.language.iso | eng | - |
| dc.publisher | The Graduate School, Ajou University | - |
| dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
| dc.title | Prognostic reappraisal of postoperative carcinoembryonic antigen in T1-2N0 colorectal cancer | - |
| dc.type | Thesis | - |
| dc.contributor.affiliation | 아주대학교 일반대학원 | - |
| dc.contributor.alternativeName | PIAN GUANGZHE | - |
| dc.contributor.department | 일반대학원 의학과 | - |
| dc.date.awarded | 2022. 2 | - |
| dc.description.degree | Doctoral | - |
| dc.identifier.localId | 1244982 | - |
| dc.identifier.uci | I804:41038-000000031353 | - |
| dc.identifier.url | https://dcoll.ajou.ac.kr/dcollection/common/orgView/000000031353 | - |
| dc.subject.keyword | Colorectal cancer | - |
| dc.subject.keyword | postoperative CEA. | - |
| dc.subject.keyword | preoperative CEA | - |
| dc.subject.keyword | preoperative CEA/tumor size | - |
| dc.description.alternativeAbstract | Background/Aim: The purpose of this study was to compare the prognostic value of preoperative carcinoembryonic antigen (CEA), preoperative CEA/tumor size and postoperative CEA in stage I colorectal cancer. Patients and Methods: We analyzed a total of 305 consecutive stage I colorectal cancer patients who underwent a radical surgery at our Department. The patients were divided into low and high preoperative CEA groups, low and high preoperative CEA/tumor size groups, and low and high postoperative CEA groups according to the optimal cut-off values. Results: Multivariate analysis showed that postoperative CEA was independently associated with OS and DFS. However, the preoperative CEA and preoperative CEA/tumor size were not. Conclusion: The prognostic value of postoperative CEA is better than preoperative CEA and preoperative CEA/tumor size in patients with stage I colorectal cancer. Moreover, the common 5 ng/ml cut-off was not optimal for risk stratification in stage I colorectal cancer. | - |
- Appears in Collections:
- Graduate School of Ajou University > Department of Medicine > 4. Theses(Ph.D)
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
-
- License
- STATISTICS
- Total Visit :3,778,502
- Total Download :1,819
- Today View :15,003
