From the last decade there were certain advancements seen in the field of Pathology to detect various type of diseases including cancer. Artificial Intelligence(AI) and machine learning played a main role in the development of digital slides and establishment of virtual platforms for sharing this compact data between medical professionals. However digital pathology has overtaken the traditional pathology, but this field is still in the need of a fully automated system that can handle the big data models. To get digital images; microscopic slides are scanned by high quality scanners which will give images of various formats(.png, .jpg,.tiff, .svs etc.) and sizes(kilo bytes to giga bytes). Histopathology images are usually scanned at high magnification rates and are in .tiff and .svs format of gigabyte size. Handling of such large size histopathology images is not an easy task. There is a need of a computer aided system that can analyze these images as an input directly and give results on the basis self-interpretation. Many automated cancer detection systems have been made using deep learning techniques, but size of image reduced from thousands of pixels to hundreds of pixels to fit in the deep learning model which affect the quality of an image and render output results. In this thesis I present the solution to this problem by designing classification model that can classify normal and invasive breast histopathological images . ICIAR Breast Cancer dataset has been used for training three different kind of ResNet34 models(ResNet34, ResNet 34 — With Weighted Random Sampler Model and ResNet 34 — with SMOTE Sampling Technique) using Transfer learning and achieved the highest accuracy of 96% with SMOTE Sampling Technique.