AJOU Central Library Repository: Alberta Stroke Program Early CT Score (ASPECTS)을 통한 심정지 후 환자들의 조기 신경학적 예후 예측

Graduate School of Ajou University Department of Medicine 3. Theses(Master)

Alberta Stroke Program Early CT Score (ASPECTS)을 통한 심정지 후 환자들의 조기 신경학적 예후 예측

Alternative Abstract: We aimed to evaluate the prognostic performance of bilateral ASPECTS (ASPECTS-b) to predict neurologic outcome in post cardiac arrest patients treated with targeted temperature management (TTM). We conducted a retrospective study of post cardiac arrest patients treated with TTM in two tertiary hospitals. The ASPECTS-b and GWR on brain computed tomography (CT) achieved within 6 hours of return of spontaneous resuscitation (ROSC) was measured twice from each institute. ROC curve analysis of ASPECTS-b and comparison of the ROC curve from each institute was done to assess the performance in predicting poor neurologic outcome (CPC 3-5). A total of 66 patients from institute A and 109 patients from institute B was studied. Of the total of 175 patients enrolled, 117 patients (66.9%) had poor neurologic outcome. ASPECTS-b showed good prognostic performance to predict poor neurologic outcome [AUROC 0.72 (0.64-0.80)] and was not significantly different between institutes [institute A vs. institute B, AUROC 0.83 (95%CI 0.72-0.94) vs. AUROC 0.73(95%CI 0.64-0.83), p=0.2]. ASPECTS-b measured from initial brain CT not only expressed good performance in predicting poor neurologic outcomes in post cardiac arrest patients, but showed similar performances between two different institutes.

Appears in Collections:: Graduate School of Ajou University > Department of Medicine > 3. Theses(Master)

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