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ST분절 상승 급성심근경색의 일차적 관상동맥중재시술에서 혈전흡인술의 효과와 미세혈관저항과의 연관성
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 탁승제 | - |
| dc.contributor.author | Woo, Seong Ill | - |
| dc.date.accessioned | 2019-10-21T07:24:11Z | - |
| dc.date.available | 2019-10-21T07:24:11Z | - |
| dc.date.issued | 2014-08 | - |
| dc.identifier.other | 17302 | - |
| dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/18586 | - |
| dc.description | 학위논문(박사)--아주대학교 일반대학원 :의학과,2014. 8 | - |
| dc.description.tableofcontents | ABSTRACT i TABLE OF CONTENTS iii LIST OF FIGURES iv LIST OF TABLES v Ⅰ. INTRODUCTION 1 Ⅱ. MATERIALS AND METHODS 2 A. PATIENTS 2 B. STUDY PROTOCOL AND PROCEDURE 2 C. PHYSIOLOGICAL ASSESSMENT 3 D. ANGIOGRAPHY 4 F. ECHOCARDIOGRAPHIC ANALYSIS 4 G. BLOOD SAMPLES 4 H. CORONARY RISK FACTORS 5 I. STATISTICAL ANALYSIS 5 Ⅲ. RESULTS 6 A. BASELINE CHARACERRISTICS 6 B. ANGIOGRAPHIC AND PERIPROCEDURAL FINDINGS 8 C. PHYSIOLOGIC AND ECHOCARDIOGRAPHIC FINDINGS 11 Ⅳ. DISCUSSION 14 V. LIMITATIONS 17 ⅤI. CONCLUSION 18 REFERENCES 19 국문요약 | - |
| dc.language.iso | eng | - |
| dc.publisher | The Graduate School, Ajou University | - |
| dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
| dc.title | ST분절 상승 급성심근경색의 일차적 관상동맥중재시술에서 혈전흡인술의 효과와 미세혈관저항과의 연관성 | - |
| dc.type | Thesis | - |
| dc.contributor.affiliation | 아주대학교 일반대학원 | - |
| dc.contributor.department | 일반대학원 의학과 | - |
| dc.date.awarded | 2014. 8 | - |
| dc.description.degree | Doctoral | - |
| dc.identifier.localId | 652574 | - |
| dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000017302 | - |
| dc.subject.keyword | coronary flow | - |
| dc.subject.keyword | primary angioplasty | - |
| dc.subject.keyword | STEMI | - |
| dc.description.alternativeAbstract | Aims: We aimed to investigate whether thrombus aspiration could preserve the index of microcirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). Methods and results: Sixty-three patients with STEMI were randomised into 2 groups: primary PCI after thrombus aspiration (aspiration group, n=33) and primary PCI without thrombus aspiration (non-aspiration group, n=30). IMR was measured using the pressure-temperature sensor-tipped coronary wire. Echocardiography were performed at baseline and at six-month follow-up. No significant differences in baseline ejection fraction (EF, 47.3±8.5% vs. 49.5±7.8%, p=0.281) and baseline wall motion score index (WMSI, 1.45±0.31 vs. 1.37±0.27, p=0.299) were observed between the two groups. However, significant differences in IMR (23.5±10.2 U vs. 34.2±21.7 U, p=0.018), ∆EF (follow-up EF - baseline EF; 3.33±4.6% vs. 0.73±1.9%, p=0.005), and ∆WMSI (follow-up WMSI – baseline WMSI; -0.121±0.16 vs. -0.004±0.07, p=0.001) were observed between the two groups. Conclusions: Thrombus aspiration as an adjunctive method to primary PCI for STEMI may preserve microvascular integrity and have beneficial effects on myocardial microcirculation. | - |
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