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펜타닐 유도성 기침의 예방을 위한 약물적 혹은 비약물적 중재법: 메타분석
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 김종엽 | - |
| dc.contributor.author | Kim, Ji Eun | - |
| dc.date.accessioned | 2019-10-21T07:23:46Z | - |
| dc.date.available | 2019-10-21T07:23:46Z | - |
| dc.date.issued | 2014-08 | - |
| dc.identifier.other | 17473 | - |
| dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/18517 | - |
| dc.description | 학위논문(박사)--아주대학교 일반대학원 :의학과,2014. 8 | - |
| dc.description.tableofcontents | ABSTRACT ⅰ TABLE OF CONTENTS ⅱ LIST OF FIGURES ⅲ LIST OF TABLES ⅳ Ⅰ. INTRODUCTION 1 Ⅱ. MATERIALS AND METHODS 2 STATISTICAL ANALYSIS 2 Ⅲ. RESULTS 4 Ⅳ. DISCUSSION 17 Ⅴ. CONCLUSION 20 REFERENCES 21 국문요약 25 | - |
| dc.language.iso | eng | - |
| dc.publisher | The Graduate School, Ajou University | - |
| dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
| dc.title | 펜타닐 유도성 기침의 예방을 위한 약물적 혹은 비약물적 중재법: 메타분석 | - |
| dc.title.alternative | Kim, Ji Eun | - |
| dc.type | Thesis | - |
| dc.contributor.affiliation | 아주대학교 일반대학원 | - |
| dc.contributor.alternativeName | Kim, Ji Eun | - |
| dc.contributor.department | 일반대학원 의학과 | - |
| dc.date.awarded | 2014. 8 | - |
| dc.description.degree | Doctoral | - |
| dc.identifier.localId | 652807 | - |
| dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000017473 | - |
| dc.subject.keyword | Anesthesia | - |
| dc.subject.keyword | Fentanyl-induced cough | - |
| dc.subject.keyword | Meta-analysis | - |
| dc.subject.keyword | Prevention | - |
| dc.description.alternativeAbstract | Fentanyl-induced cough (FIC) is often observed after intravenous bolus administration of fentanyl during anesthesia induction. This meta-analysis assessed the efficacy of pharmacological and non-pharmacological interventions to reduce the incidence of FIC. We searched for randomized controlled trials comparing the pharmacological or non-pharmacological interventions with the controls to prevent FIC; we included 28 studies retrieved from Pub-Med, Embase, and Cochrane Library. Overall incidence of FIC was approximately 31%. Lidocaine [odds ratio (OR) = 0.29, 95% confidence interval (CI) 0.21 –0.39], N-methyl-D-aspartate (NMDA) receptor antagonists [OR = 0.09, 95% CI 0.02 – 0.42], propofol [OR = 0.07, 95% CI 0.01 – 0.36], α2 agonists [OR = 0.32, 95% CI 0.21 – 0.48], β2 agonists [OR = 0.10, 95% CI 0.03 – 0.30], fentanyl priming [OR = 0.33, 95% CI 0.19 – 0.56], and slow injection of fentanyl [OR = 0.25, 95% CI 0.11 – 0.58)] were effective in decreasing the incidence of FIC, whereas atropine [OR = 1.10, 95% CI 0.58 – 2.11] and benzodiazepines [OR = 2.04, 95% CI 1.33 – 3.13] were not effective. This meta-analysis found that lidocaine, NMDA receptor antagonists, propofol, α2 agonists, β2 agonists, and priming dose of fentanyl were effective in preventing FIC, but atropine and benzodiazepines were not. Slow injection of fentanyl was effective in preventing FIC, but results depend on the speed of administration. | - |
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