화장품 적용을 위한 피커링 에멀젼 특성 연구

Author(s)
권육영
Advisor
이평천
Department
일반대학원 응용생명공학과
Publisher
The Graduate School, Ajou University
Publication Year
2019-02
Language
kor
Alternative Abstract
Characteristics of Pickering Emulsion were systematically analyzed for cosmetic application. Analytical conditions were optimized of Arbutin (whitening ingredient) and Ceramides (intercellular lipid) to verify the functionality of them. The transdermal absorption of 24 hours was measured by franz diffusion cell, and the transdermal absorption of active ingredient was determination by HPLC and ESI-MS compared with the classic emulsion. In the O/W formulation contain Arbutin, the pickering emulsion showed active ingredients are 50% higher skin absorption and 100% higher skin residual, in the W/O formulation contain Ceramides, pickering emulsion were 0.022~0.08 (ug/ml) and classic emulsion 0.017~0.102 (ug/ml), both formulations showed similar value of net transferred ceramide concentration. Based on observed stability of Zeta potential and each temperature for 2 months of the visual test, all four formulations were stable. In addition, applying them as new cosmetic formulations that can differentiate in usability of “Water in Air” identified products with marketability.
URI
https://dspace.ajou.ac.kr/handle/2018.oak/15178
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Graduate School of Ajou University > Department of Applied Biotechnology > 3. Theses(Master)
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