화장품 적용을 위한 피커링 에멀젼 특성 연구

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dc.contributor.advisor이평천-
dc.contributor.author권육영-
dc.date.accessioned2019-04-01T16:42:05Z-
dc.date.available2019-04-01T16:42:05Z-
dc.date.issued2019-02-
dc.identifier.other28317-
dc.identifier.urihttps://dspace.ajou.ac.kr/handle/2018.oak/15178-
dc.description학위논문(석사)--아주대학교 일반대학원 :응용생명공학과,2019. 2-
dc.description.tableofcontents제1장.서론 1 제1절.연구의 목적 및 필요성 1 제2절.이론적 배경 4 1. 피커링 에멀젼 (Pickering emulsion) 4 2. 알부틴(Arbutin) 8 3. 세라마이드(Ceramide) 와 피부 10 제2장.재료 및 방법 12 제1절.실험 재료 12 1. 재료 12 2. 실험 기기 및 제조 방법 16 제2절.실험 방법 18 1. O/W 및 W/O 유화제형 Formulation 18 2. Franz Cell을 이용한 피부 흡수력 테스트 20 3. HPLC를 이용한 유효성분 분석 및 정량 분석 22 4. ES-MSI를 이용한 유효성분 분석 및 정량 분석 24 5. Zeta potential 및 온도에 따른 안정성 테스트 26 6. 독특한 사용감 제형 (Water in Air) 에의 응용 28 제3장.결과 및 고찰 29 제1절.결과 및 고찰 29 1. O/W 유화제형의 유효성분 피부 흡수력 측정 결과 29 2. W/O 유화제형의 유효성분 피부 흡수력 측정 결과 32 3. Pickering emulsion 과 Classic emulsion 비교 결과 37 4. Zeta potential 및 온도에 따른 안정성 테스트 결과 45 5. 독특한 사용감 제형 (Water in Air) 에의 응용 결과 49 제4장. 결론 51 제5장. 참고문헌 52 Abstract 55-
dc.language.isokor-
dc.publisherThe Graduate School, Ajou University-
dc.rights아주대학교 논문은 저작권에 의해 보호받습니다.-
dc.title화장품 적용을 위한 피커링 에멀젼 특성 연구-
dc.typeThesis-
dc.contributor.affiliation아주대학교 일반대학원-
dc.contributor.department일반대학원 응용생명공학과-
dc.date.awarded2019. 2-
dc.description.degreeMaster-
dc.identifier.localId905582-
dc.identifier.uciI804:41038-000000028317-
dc.identifier.urlhttp://dcoll.ajou.ac.kr:9080/dcollection/common/orgView/000000028317-
dc.description.alternativeAbstractCharacteristics of Pickering Emulsion were systematically analyzed for cosmetic application. Analytical conditions were optimized of Arbutin (whitening ingredient) and Ceramides (intercellular lipid) to verify the functionality of them. The transdermal absorption of 24 hours was measured by franz diffusion cell, and the transdermal absorption of active ingredient was determination by HPLC and ESI-MS compared with the classic emulsion. In the O/W formulation contain Arbutin, the pickering emulsion showed active ingredients are 50% higher skin absorption and 100% higher skin residual, in the W/O formulation contain Ceramides, pickering emulsion were 0.022~0.08 (ug/ml) and classic emulsion 0.017~0.102 (ug/ml), both formulations showed similar value of net transferred ceramide concentration. Based on observed stability of Zeta potential and each temperature for 2 months of the visual test, all four formulations were stable. In addition, applying them as new cosmetic formulations that can differentiate in usability of “Water in Air” identified products with marketability.-
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Graduate School of Ajou University > Department of Applied Biotechnology > 3. Theses(Master)
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