Understanding how transport infrastructure actually stimulates trade in Cameroon and consequently economic growth, may offer a valuable insight for policies that boost trade. Bilateral trade relations among the union of Central African Monetary and Economic countries is relatively low compared to trade in other economic blocks in Africa. With the use of an empirical analysis, this study investigate the association between trade, transport infrastructure and economic growth in Cameroon within a timeline, allowing to control for unobservable individual specific characteristics that affect trade. This study has as results that show that belonging to CEMAC has increased transport infrastructure and trade between member countries. The results also point out the importance of geographical distance as well as being landlocked as barriers to trade within the Central African region.