높은 이완성을 갖는 새로운 시스템의 MR 조영제: 가돌리늄을 담지한 메조다공 실리카 코어/쉘

DC Field Value Language
dc.contributor.advisor김상욱-
dc.contributor.author김민정-
dc.date.accessioned2018-11-08T08:05:20Z-
dc.date.available2018-11-08T08:05:20Z-
dc.date.issued2012-02-
dc.identifier.other12169-
dc.identifier.urihttps://dspace.ajou.ac.kr/handle/2018.oak/10335-
dc.description학위논문(석사)아주대학교 일반대학원 :분자과학기술학과,2012. 2-
dc.description.tableofcontentsCover page ________________________________________1 Approval page _____________________________________3 Acknowledgements ________________________________4 Abstract ___________________________________________5 Table of Contents __________________________________6 List of Scheme ____________________________________7 List of Figures _____________________________________8 Introduction _______________________________________9 Experimental Section ______________________________11 Results and Discussion ____________________________15 Conclusions ______________________________________18 Scheme __________________________________________19 Figure ____________________________________________20 References _______________________________________28-
dc.language.isoeng-
dc.publisherThe Graduate School, Ajou University-
dc.rights아주대학교 논문은 저작권에 의해 보호받습니다.-
dc.title높은 이완성을 갖는 새로운 시스템의 MR 조영제: 가돌리늄을 담지한 메조다공 실리카 코어/쉘-
dc.typeThesis-
dc.contributor.affiliation아주대학교 일반대학원-
dc.contributor.department일반대학원 분자과학기술학과-
dc.date.awarded2012. 2-
dc.description.degreeMaster-
dc.identifier.localId569814-
dc.identifier.urlhttp://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000012169-
dc.subject.keyword조영제-
dc.subject.keyword가돌리늄-
dc.subject.keyword실리카-
dc.description.alternativeAbstractNew system of gadolinium based nanoparticles for T1-MR contrast agents which have high T1-relaxivity was developed. It showed non-aggregated, biocompatible properties and no release of free Gd3+ ions. The structure of non-aggregated MSHS/Gd2O3@pAA system was elucidated by TEM and SEM. The specific relaxivities, r1 and r2 values, of the MSHS/Gd2O3@pAA are measured by 4.9T MR scanner, which are higher than those of the commercial Gadovist. Gd3+ ion releasing experiment was conducted by measuring an amount of leached Gd3+, which showed a trace of ions was released. The cytotoxicity of MSHS/Gd2O3@pAA was examined on MDA-MB 435S cells, which showed no appreciable toxicity in the cells.-
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Graduate School of Ajou University > Department of Molecular Science and Technology > 3. Theses(Master)
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