높은 이완성을 갖는 새로운 시스템의 MR 조영제: 가돌리늄을 담지한 메조다공 실리카 코어/쉘
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 김상욱 | - |
dc.contributor.author | 김민정 | - |
dc.date.accessioned | 2018-11-08T08:05:20Z | - |
dc.date.available | 2018-11-08T08:05:20Z | - |
dc.date.issued | 2012-02 | - |
dc.identifier.other | 12169 | - |
dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/10335 | - |
dc.description | 학위논문(석사)아주대학교 일반대학원 :분자과학기술학과,2012. 2 | - |
dc.description.tableofcontents | Cover page ________________________________________1 Approval page _____________________________________3 Acknowledgements ________________________________4 Abstract ___________________________________________5 Table of Contents __________________________________6 List of Scheme ____________________________________7 List of Figures _____________________________________8 Introduction _______________________________________9 Experimental Section ______________________________11 Results and Discussion ____________________________15 Conclusions ______________________________________18 Scheme __________________________________________19 Figure ____________________________________________20 References _______________________________________28 | - |
dc.language.iso | eng | - |
dc.publisher | The Graduate School, Ajou University | - |
dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
dc.title | 높은 이완성을 갖는 새로운 시스템의 MR 조영제: 가돌리늄을 담지한 메조다공 실리카 코어/쉘 | - |
dc.type | Thesis | - |
dc.contributor.affiliation | 아주대학교 일반대학원 | - |
dc.contributor.department | 일반대학원 분자과학기술학과 | - |
dc.date.awarded | 2012. 2 | - |
dc.description.degree | Master | - |
dc.identifier.localId | 569814 | - |
dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000012169 | - |
dc.subject.keyword | 조영제 | - |
dc.subject.keyword | 가돌리늄 | - |
dc.subject.keyword | 실리카 | - |
dc.description.alternativeAbstract | New system of gadolinium based nanoparticles for T1-MR contrast agents which have high T1-relaxivity was developed. It showed non-aggregated, biocompatible properties and no release of free Gd3+ ions. The structure of non-aggregated MSHS/Gd2O3@pAA system was elucidated by TEM and SEM. The specific relaxivities, r1 and r2 values, of the MSHS/Gd2O3@pAA are measured by 4.9T MR scanner, which are higher than those of the commercial Gadovist. Gd3+ ion releasing experiment was conducted by measuring an amount of leached Gd3+, which showed a trace of ions was released. The cytotoxicity of MSHS/Gd2O3@pAA was examined on MDA-MB 435S cells, which showed no appreciable toxicity in the cells. | - |
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