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4시간 후 혈청 아밀라아제와 리파아제 농도를 이용한 내시경 역행성 췌담도 조영술 이후 췌장염 발생의 예측
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 김진홍 | - |
| dc.contributor.author | Lee, Yeon Kyung | - |
| dc.date.accessioned | 2019-10-21T07:25:08Z | - |
| dc.date.available | 2019-10-21T07:25:08Z | - |
| dc.date.issued | 2015-08 | - |
| dc.identifier.other | 20149 | - |
| dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/18676 | - |
| dc.description | 학위논문(석사)--아주대학교 일반대학원 :의학과,2015. 8 | - |
| dc.description.tableofcontents | ABSTRACT INTRODUCTION MATERIALS AND METHODS RESULTS CONCLUSION REFERENCE 국문요약 | - |
| dc.language.iso | eng | - |
| dc.publisher | The Graduate School, Ajou University | - |
| dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
| dc.title | 4시간 후 혈청 아밀라아제와 리파아제 농도를 이용한 내시경 역행성 췌담도 조영술 이후 췌장염 발생의 예측 | - |
| dc.title.alternative | Prediction of Post-ERCP Pancreatitis | - |
| dc.type | Thesis | - |
| dc.contributor.affiliation | 아주대학교 일반대학원 | - |
| dc.contributor.alternativeName | Yeon Kyung Lee | - |
| dc.contributor.department | 일반대학원 의학과 | - |
| dc.date.awarded | 2015. 8 | - |
| dc.description.degree | Master | - |
| dc.identifier.localId | 705392 | - |
| dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000020149 | - |
| dc.subject.keyword | 급성췌장염 | - |
| dc.subject.keyword | 내시경 역행성 췌담도 조영술 | - |
| dc.subject.keyword | 고아밀라아제혈증 | - |
| dc.description.alternativeAbstract | Background & Aims : Acute pancreatitis is the most common, serious complication of endoscopic retrograde cholangiopancreatography (ERCP). Early prediction of post-ERCP pancreatitis (PEP) could enable earlier safe discharge of patients on the same day after ERCP. This study investigated a predictive cut-off value of 4-hour post-ERCP serum amylase and lipase levels for PEP. Methods : We retrospectively evaluated patients who underwent ERCP procedures and testing for serum amylase and lipase 4-hours after ERCP and the next morning at Ajou Medical Center from January 2012 to August 2013. We studied; patient demographics, procedure reasons, pancreatogram performance, and serum amylase and lipase levels. Results : PEP occurred in 16 (3.1%) patients after 516 ERCP procedures. Its severity was mild in 4 (25%), moderate in 9 (56.3%), and severe in 3 (18.8%). Mean 4-hour amylase level was significantly higher in patients with PEP; than in those without (965 U/L vs. 158 U/L, P = .001). No statistically significant differences occurred in age, sex, and procedure reasons between both groups. Sensitivity, specificity and negative predictive value (NPV) of 4-hour post-ERCP amylase level with a cut-off value of 2.5x upper limit of reference (ULR) (290 U/L) were 39.1%, 98.5% and 97.2%, respectively; with a cut-off value of 8× ULR (480 U/L), they were 60.0%, 97.5% and 99.6%. The patient group undergoing pancreatogram had a high incidence of PEP; but no significant difference in 4-hour post-ERCP serum amylase and lipase, compared with its counterpart. Conclusions : Four-hour post-ERCP serum amylase and lipase levels with cut-off values of 2.5x and 8x ULR are proven useful predictive values for earlier safe discharge of patients on the same day after ERCP. | - |
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- Graduate School of Ajou University > Department of Medicine > 3. Theses(Master)
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