This study was designed to evaluate whether a computed tomography (CT) protocol without an unenhanced phase could be used for the diagnosis of appendicitis in pediatric patients who visited the emergency department (ED) with acute non-traumatic right lower abdominal pain.
We retrospectively selected 100 samples from pediatric abdominal CT scans which were performed in the ED and read by pediatric radiologists. 30 emergency physicians were separately asked to evaluate those samples twice. The first evaluation was performed without the unenhanced phase (protocol A). The second evaluation was performed with both of the unenhanced phase and the contrast-enhanced phase (protocol B). The sensitivity and specificity of each protocol for the diagnosis of suspected acute appendicitis were determined. Intraobserver and interobserver agreements were measured using kappa statistics.
The mean sensitivity and specificity of the two protocols were similar to each other. The sensitivities of protocol A and protocol B were 97.13 % [95% Confidence interval = 96.13-98.14] and 97.60 % [96.67-98.53], respectively. The specificities of protocol A and protocol B were 95.47% [94.34-96.59] and 94.67% [93.33-96.00], respectively. The mean kappa value for intraobserver agreement between results from the two protocols was 0.91 [0.88-0.93]. The kappa value for the interobserver agreement was 0.90 [0.89-0.91] for protocol A and 0.87[0.86-0.88] for protocol B.
It is feasible to take a CT scan without an unenhanced phase for evaluating suspected appendicitis in children with abdominal pain visiting the ED.