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Propofol 목표농도조절주입 중 경비 또는 경구 기관내 삽관을 위한 remifentanil의 효과처농도 비교
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 김종엽 | - |
| dc.contributor.author | Choi, Yi Hwa | - |
| dc.date.accessioned | 2019-10-21T07:17:58Z | - |
| dc.date.available | 2019-10-21T07:17:58Z | - |
| dc.date.issued | 2011-02 | - |
| dc.identifier.other | 11257 | - |
| dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/17926 | - |
| dc.description | 학위논문(석사)--아주대학교 대학원 일반대학원 :의학과,2011. 2 | - |
| dc.description.tableofcontents | ABSTRACTⅰ TABLE OF CONTENTSⅱ LIST OF FIGURES ⅲ LIST OF TABLESⅳ TEXTⅴ Ⅰ. INTRODUCTION1 Ⅱ. METHODS 2 Ⅲ. RESULTS 6 Ⅳ. DISCUSSION 9 V. CONCLUSION 17 REFERENCES ⅵ 국문요약 ⅶ | - |
| dc.language.iso | eng | - |
| dc.publisher | The Graduate School, Ajou University | - |
| dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
| dc.title | Propofol 목표농도조절주입 중 경비 또는 경구 기관내 삽관을 위한 remifentanil의 효과처농도 비교 | - |
| dc.title.alternative | Effect-site Concentration of Remifentanil for Nasotracheal versus Orotracheal Intubation during Propofol Target-controlled Infusion | - |
| dc.type | Thesis | - |
| dc.contributor.affiliation | 아주대학교 일반대학원 | - |
| dc.contributor.alternativeName | Choi, Yi-Hwa | - |
| dc.contributor.department | 일반대학원 의학과 | - |
| dc.date.awarded | 2011. 2 | - |
| dc.description.degree | Master | - |
| dc.identifier.localId | 569438 | - |
| dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011257 | - |
| dc.subject.keyword | Remifentanil | - |
| dc.subject.keyword | Propofol | - |
| dc.subject.keyword | Orotracheal intubation | - |
| dc.subject.keyword | Nasotracheal intubation | - |
| dc.description.alternativeAbstract | Background: The purpose of this study was to determine the effect-site concentrations of remifentanil required for acceptable nasotracheal (NT) intubation in adults after propofol target-controlled infusion (TCI) without neuromuscular blocking agent, and whether or not these concentrations differ from those for orotracheal (OT) intubation. Methods: Fifty patients were assigned to receive either OT intubation (OT group, n = 25) or NT intubation (NT group, n = 25). Anaesthesia was induced with propofol TCI at the effect-site concentration of 5.0 μg/ml. Two minutes later, the predetermined effect-site concentration of remifentanil was started (from 4.5 ng/ml) using Dixon’s up-and-down method. Tracheal intubation was performed during the remifentanil infusion 2 min after beginning. Acceptable intubation was defined as excellent or good intubating conditions. Results: EC50 ± SD of remifentanil in the OT and NT groups was 5.58 ± 0.75 ng/ml and 6.08 ± 0.75 ng/ml, respectively; there was no statistical significance between the groups (P = 0.277). Using isotonic regression, EC50 (95% CI) of remifentanil in the OT and NT groups was 5.00 (3.34-7.46) ng/ml and 5.75 (3.66-7.84) ng/mlv, respectively (P = 0.592). Conclusion: The effect-site concentration of remifentanil for acceptable NT intubation was 6.08 ng/ml in 50% of adults during propofol TCI at an effect-site concentration of 5.0 μg/ml without neuromuscular blocking agent. The predicted effect-site concentration of remifentanil for NT intubation was not different from OT intubation. | - |
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- Graduate School of Ajou University > Department of Medicine > 3. Theses(Master)
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