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저신장증 소아에서 체질량 지수가 성장호르몬
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 황진순, 배기수, 정조원 | - |
| dc.contributor.author | Lee, Hea Sang | - |
| dc.date.accessioned | 2019-10-21T07:17:23Z | - |
| dc.date.available | 2019-10-21T07:17:23Z | - |
| dc.date.issued | 2011-02 | - |
| dc.identifier.other | 11196 | - |
| dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/17829 | - |
| dc.description | 학위논문(석사)--아주대학교 일반대학원 :의학과,2011. 2 | - |
| dc.description.tableofcontents | ABSTRACT i TABLE OF CONTENTS ii LIST OF FIGURES iii LIST OF TABLES iv I. INTRODUCTION 1 II. MATERIALS AND METHODS 2 A. SUBJECTS 2 B. STUDY DESIGN 2 C. LABORATORY MEASUREMENTS 3 D. STATISTICAL ANALYSIS 4 III. RESULTS 5 A. SUBJECTS CHARACTERISTICS 5 B. COMPARISON OF GH RESPONSES OF INSULIN VS. DOPAMINE AND CLONIDINE 5 C. DETERMINANTS OF PEAK GROWTH HORMONE RESPONSE TO PHARMACOLOGICAL TESTS 6 PHARMACOLOGICAL TESTS 6 D. RELIABILITY OF TESTS 6 IV. DISCUSSION 12 V. CONCLUSION 15 REFERENCES 16 국문요약 21 | - |
| dc.language.iso | eng | - |
| dc.publisher | The Graduate School, Ajou University | - |
| dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
| dc.title | 저신장증 소아에서 체질량 지수가 성장호르몬 | - |
| dc.title.alternative | Influence of Body Mass Index on Growth Hormone Responses to Classic Provocative Tests in Children with Short Stature | - |
| dc.type | Thesis | - |
| dc.contributor.affiliation | 아주대학교 일반대학원 | - |
| dc.contributor.alternativeName | Hae Sang Lee | - |
| dc.contributor.department | 일반대학원 의학과 | - |
| dc.date.awarded | 2011. 2 | - |
| dc.description.degree | Master | - |
| dc.identifier.localId | 569251 | - |
| dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011196 | - |
| dc.subject.keyword | Body mass index | - |
| dc.subject.keyword | Growth hormone | - |
| dc.subject.keyword | Short stature | - |
| dc.subject.keyword | 체질량지수 | - |
| dc.subject.keyword | 성장호르몬 | - |
| dc.subject.keyword | 저신장 | - |
| dc.description.alternativeAbstract | Objective: Growth hormone (GH) secretion is regulated by physiological parameters. Obesity is associated with diminished spontaneous and stimulated GH secretion. The aim of this study was to assess the influence of BMI on growth hormone response to provocative testing in children with short stature. Materials and methods: Clinical data was collected retrospectively by chart review from the Pediatric Endocrine Unit at Ajou University Hospital. A total of 187 subjects with short stature who completed a GH stimulation testing between 2003 and 2009 were included in the study. Results: The study population included 123 (65.8%) males and 64 (34.2%) females with a mean age of 8.5 ± 2.9 years. Of the 187 subjects, 66 (35.3%) had GH deficiency (serum peak GH <10 ng/ml), while 121 (64.7%) were categorized as having idiopathic short stature (serum peak GH ≥ 10 ng/ml). In a stepwise multivariate analysis, BMI was a significantly independent predictor of peak GH. Elevated BMI was negatively associated with peak plasma GH levels. Conclusion: Higher BMI is associated with lower GH secretion. BMI should be measured and GH results appropriately interpreted for all subject undergoing GH stimulation testing. | - |
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- Graduate School of Ajou University > Department of Medicine > 3. Theses(Master)
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