Alfentanil과 remifentanil 정주 후 나타나는 기침의 발생 빈도와 정도 비교

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dc.contributor.advisor이숙영-
dc.contributor.authorCho, Han Bum-
dc.date.accessioned2019-10-21T07:17:20Z-
dc.date.available2019-10-21T07:17:20Z-
dc.date.issued2011-02-
dc.identifier.other11484-
dc.identifier.urihttps://dspace.ajou.ac.kr/handle/2018.oak/17821-
dc.description학위논문(박사)--아주대학교 일반대학원 :의학과,2011. 2-
dc.description.tableofcontentsABSTRACT i TABLE OF CONTENTS ii LIST OF TABLES iii LIST OF FIGURE iv ABBREVIATIONS v I. INTRODUCTION 1 II. PATIENTS AND METHODS 3 III. RESULTS 5 IV. DISCUSSION 12 REFERENCES 17 국문요약 21-
dc.language.isoeng-
dc.publisherThe Graduate School, Ajou University-
dc.rights아주대학교 논문은 저작권에 의해 보호받습니다.-
dc.titleAlfentanil과 remifentanil 정주 후 나타나는 기침의 발생 빈도와 정도 비교-
dc.title.alternativeHan Bum Cho-
dc.typeThesis-
dc.contributor.affiliation아주대학교 일반대학원-
dc.contributor.alternativeNameHan Bum Cho-
dc.contributor.department일반대학원 의학과-
dc.date.awarded2011. 2-
dc.description.degreeMaster-
dc.identifier.localId569235-
dc.identifier.urlhttp://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011484-
dc.subject.keywordalfentanil-
dc.subject.keywordremifentanil-
dc.subject.keywordopioid induced cough-
dc.description.alternativeAbstractIntroduction: Intravenous administration of fentanyl derivatives can induce cough paradoxically. This study examined the incidence and severity of cough after a bolus of alfentanil and remifentanil. Methods: Four-hundred sixty five patients, aged 18-70 years, were allocated randomly to three groups to receive alfentanil 10 μg/kg, remifentanil 1 μg/kg, or an equal volume of 0.9% saline intravenously over 10 s. Any episode of cough was classified as coughing and graded as mild (1-2), moderate (3-4) or severe (5 or more). Results: The overall incidence of cough was higher in the opioid groups than the saline group. The remifentanil group [39/150 patients; 26.0%, (95% CI, 19.6-33.6%)] showed a higher incidence than the alfentanil group [11/152 patients; 7.2%, (95% CI, 0.4-12.6%)] (P < 0.001). There was no significant difference in the severity of cough between alfentanil and remifentanil group. Conclusion: This study demonstrated that the equipotent boluses of alfentanil and remifentanil induced coughing, even though the incidence of cough after alfentanil administration was lower than that after remifentanil administration.-
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Graduate School of Ajou University > Department of Medicine > 3. Theses(Master)
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