Alfentanil과 remifentanil 정주 후 나타나는 기침의 발생 빈도와 정도 비교
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 이숙영 | - |
dc.contributor.author | Cho, Han Bum | - |
dc.date.accessioned | 2019-10-21T07:17:20Z | - |
dc.date.available | 2019-10-21T07:17:20Z | - |
dc.date.issued | 2011-02 | - |
dc.identifier.other | 11484 | - |
dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/17821 | - |
dc.description | 학위논문(박사)--아주대학교 일반대학원 :의학과,2011. 2 | - |
dc.description.tableofcontents | ABSTRACT i TABLE OF CONTENTS ii LIST OF TABLES iii LIST OF FIGURE iv ABBREVIATIONS v I. INTRODUCTION 1 II. PATIENTS AND METHODS 3 III. RESULTS 5 IV. DISCUSSION 12 REFERENCES 17 국문요약 21 | - |
dc.language.iso | eng | - |
dc.publisher | The Graduate School, Ajou University | - |
dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
dc.title | Alfentanil과 remifentanil 정주 후 나타나는 기침의 발생 빈도와 정도 비교 | - |
dc.title.alternative | Han Bum Cho | - |
dc.type | Thesis | - |
dc.contributor.affiliation | 아주대학교 일반대학원 | - |
dc.contributor.alternativeName | Han Bum Cho | - |
dc.contributor.department | 일반대학원 의학과 | - |
dc.date.awarded | 2011. 2 | - |
dc.description.degree | Master | - |
dc.identifier.localId | 569235 | - |
dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011484 | - |
dc.subject.keyword | alfentanil | - |
dc.subject.keyword | remifentanil | - |
dc.subject.keyword | opioid induced cough | - |
dc.description.alternativeAbstract | Introduction: Intravenous administration of fentanyl derivatives can induce cough paradoxically. This study examined the incidence and severity of cough after a bolus of alfentanil and remifentanil. Methods: Four-hundred sixty five patients, aged 18-70 years, were allocated randomly to three groups to receive alfentanil 10 μg/kg, remifentanil 1 μg/kg, or an equal volume of 0.9% saline intravenously over 10 s. Any episode of cough was classified as coughing and graded as mild (1-2), moderate (3-4) or severe (5 or more). Results: The overall incidence of cough was higher in the opioid groups than the saline group. The remifentanil group [39/150 patients; 26.0%, (95% CI, 19.6-33.6%)] showed a higher incidence than the alfentanil group [11/152 patients; 7.2%, (95% CI, 0.4-12.6%)] (P < 0.001). There was no significant difference in the severity of cough between alfentanil and remifentanil group. Conclusion: This study demonstrated that the equipotent boluses of alfentanil and remifentanil induced coughing, even though the incidence of cough after alfentanil administration was lower than that after remifentanil administration. | - |
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